I would like to dedicate this blog to all the intensivists who are keen to expand their scientific armamentarium. I hope this blog would enable us to discuss and share experiences in the field of Critical Care Medicine.
Regards,
Dr.Bhargav Mundlapudi
This week we shall be discussing about dengue hemorrhagic fevers
ReplyDeleteDoes N-acetylecysteine help in dengue hepatitis?
DeleteN-acetylcysteine has been shown effective in small case studies in dengue induced acute hepatitis in virtue of its hepatoprotective effect, antioxidant and anticytokine and anti inflammatory properties.It might suppress relatively the cytokine strom, which is believed to be the major pathway in dengue hemorrhagic fevers leading to multiorgan failure.But there is no randomised control trails conducted on the same
ReplyDeleteHimaal -Good work dr bhargav
ReplyDeleteSmall case studies by kumar et.al and mumtaz et.al showed that when N-acetylcysteine given in early dengue induced acute hepatic failure in grade 1 to grade 2 hepatic encephalopathy, the outcomes are better and many of the patients did survive.
ReplyDeleteRecently we have been getting cases of pancreatitis as a sequelae to dengue fever...none survived...any views on this...please share
ReplyDeletePost dengue pancreatis is a known entity.its believed to be secondary to some auto immune process triggered during the dengue infestation. Likewise dengue induced myocarditis
DeleteThere are some isolated case reports regarding pancreatitis complicating dengue fevers.kindly look at this link
Deletehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049044/
Role of vit k in DHL? ,
ReplyDeleteIts expected to have mild to severe hepatic dysfunction in dengue with impaired vit k dependent factor production with coagulopathy evident by prolonged PT and APTT.It may be prudent to give a trail of vit k in such instance or in case of active bleeding
DeleteJust a query? Can cholecystitis associated with dengue be the cause for pancreatitis? Apart from the autoimmune process
ReplyDeleteIts possible that retrograde inflammation can spread from gall bladder to pancreatic duct leading to pancreatitis, even a micro calculi getting dislodged in the face of active inflammation down to pancreatic duct
DeleteVery Informative blog!
ReplyDeleteGlad to visit this blog!
We can search for Best Oncologist in Bangalore on cancer doctor in Bangalore
Are you searching for the best treatment for diabetes? Then you should visit our site. Because we provide the best treatment for diabetes. Best diabetes treatment
ReplyDelete